pathml

Unify computational pathology workflows for whole-slide images and related data.

1|Updated Mar 4, 2026
One-click install
npx skills add https://github.com/Hung-3008/agusta --skill pathml-hung-3008
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: pathml
Source: https://github.com/Hung-3008/agusta/tree/main/.agents/skills/pathml
Command: npx skills add https://github.com/Hung-3008/agusta --skill pathml-hung-3008

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

PathML addresses the complexity of computational pathology workflows by providing an end-to-end toolkit that unifies loading, preprocessing, graph construction, ML model training, and multiparametric imaging analysis for whole-slide images and related data.

Core Features & Use Cases

  • Image loading across 160+ proprietary formats with unified interfaces and slide classes
  • Modular preprocessing pipelines including stain normalization, tissue/nucleus detection, and QC transforms
  • Graph construction to model cellular/tissue relationships for graph neural networks
  • Built-in deep learning models (HoVer-Net, HACTNet) with training, evaluation, and ONNX export
  • Multiparametric imaging support (CODEX, Vectra, MERFISH) for per-cell marker quantification
  • Data management using HDF5 storage, tile management, and distributed processing

Quick Start

Install PathML, load a slide with SlideData, generate tiles, apply a preprocessing pipeline, and save the results to an HDF5 file.

Frequently Asked Questions about pathml

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I preprocess whole-slide images for machine learning pipelines?

Preprocess whole-slide images by loading slides into a SlideData class, generating tiles, and applying modular transforms for stain normalization, tissue detection, and QC before saving to HDF5.

Can I build spatial graphs from whole-slide images for graph neural networks?

Build spatial graphs from whole-slide images by detecting nuclei and constructing cellular relationship models, enabling graph neural network training with built-in architectures like HACTNet.

Does computational pathology software support multiplex imaging formats like CODEX and MERFISH?

Computational pathology workflows support multiplex imaging formats including CODEX, Vectra, and MERFISH, enabling per-cell marker quantification alongside H&E whole-slide image analysis.

How do I manage large pathology datasets during distributed processing?

Manage large pathology datasets using HDF5 storage for tile management and distributed processing, ensuring scalable data handling across high-resolution whole-slide images and multiplex data.

What is the best way to train deep learning models for nucleus detection in pathology slides?

Train deep learning models for nucleus detection using built-in architectures like HoVer-Net, supported by comprehensive reference documentation and scalable HDF5 dataset management for evaluation and ONNX export.

Can I load proprietary whole-slide image formats using a unified interface?

Load over 160 proprietary whole-slide image formats using unified slide classes and interfaces, standardizing diverse inputs into a consistent computational pathology workflow.