pathml

Processes whole-slide pathology images with machine learning and spatial analysis.

8|Updated Nov 19, 2025
One-click install
npx skills add https://github.com/sanand0/scientific-research --skill pathml-sanand0
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: pathml
Source: https://github.com/sanand0/scientific-research/tree/main/.claude/skills/pathml
Command: npx skills add https://github.com/sanand0/scientific-research --skill pathml-sanand0

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

This Skill automates complex computational pathology workflows, enabling advanced analysis of whole-slide images and multiparametric data without requiring deep expertise in image processing or machine learning libraries.

Core Features & Use Cases

  • Image Loading: Supports over 160 WSI formats (Aperio, Hamamatsu, DICOM, OME-TIFF).
  • Preprocessing: Stain normalization, tissue/nucleus detection, artifact labeling.
  • Machine Learning: Integrated HoVer-Net and HACTNet for nucleus segmentation and classification.
  • Spatial Analysis: Graph construction for cell-cell interactions and neighborhood analysis.
  • Use Case: Analyze a batch of H&E stained cancer slides to automatically detect, segment, and classify all nuclei, then quantify tumor-infiltrating lymphocytes and their spatial distribution.

Quick Start

Use the pathml skill to load the whole-slide image at 'path/to/slide.svs' and generate tiles of size 256x256.

Frequently Asked Questions about pathml

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I analyze whole-slide pathology images using machine learning?

Analyze whole-slide pathology images using machine learning by loading diverse WSI formats, applying stain normalization, detecting nuclei, and training deep learning models for pathology data analysis.

What whole slide imaging formats are supported for computational pathology workflows?

Computational pathology workflows support over 160 whole slide imaging formats, including Aperio, Hamamatsu, DICOM, and OME-TIFF, facilitating seamless image loading and preprocessing.

How do I automate nucleus detection and segmentation on H&E stained slides?

Automate nucleus detection and segmentation on H&E stained slides using integrated deep learning models like HoVer-Net and HACTNet for precise classification and spatial graph construction.

Can I quantify tumor-infiltrating lymphocytes and their spatial distribution from histopathology images?

Quantify tumor-infiltrating lymphocytes and their spatial distribution from histopathology images by constructing spatial graphs of cell-cell interactions and performing neighborhood analysis.

Does this computational pathology toolkit require deep expertise in image processing libraries?

This computational pathology toolkit does not require deep expertise in image processing libraries, as it automates complex workflows for whole-slide images and multiparametric data analysis.

What is the best way to preprocess pathology slides for tissue and artifact detection?

Preprocess pathology slides for tissue and artifact detection by applying stain normalization, tissue detection, and artifact labeling before generating tiles for machine learning analysis.