pathml

Analyze whole-slide pathology images with nucleus segmentation and graph construction.

1|Updated Jan 14, 2026
One-click install
npx skills add https://github.com/Sologa/codex-pipeline --skill pathml-sologa
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: pathml
Source: https://github.com/Sologa/codex-pipeline/tree/main/.codex/skills/pathml
Command: npx skills add https://github.com/Sologa/codex-pipeline --skill pathml-sologa

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

This Skill streamlines complex computational pathology workflows, enabling advanced analysis of whole-slide images and multiplexed data.

Core Features & Use Cases

  • Advanced WSI Analysis: Perform nucleus segmentation, graph construction, and ML model training on pathology data.
  • Multiplexed Imaging: Analyze CODEX and Vectra data for spatial proteomics.
  • Use Case: Analyze a whole-slide image to segment nuclei, quantify marker expression, and build a spatial graph representing cell interactions for downstream machine learning.

Quick Start

Use the pathml skill to load a whole-slide image and generate tiles for processing.

Frequently Asked Questions about pathml

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I analyze whole-slide images for nucleus segmentation and machine learning?

Whole-slide image analysis can be performed using a computational pathology toolkit to execute nucleus segmentation, tissue graph construction, and machine learning model training. It supports over 160 slide formats and integrates with HDF5 for data management.

What is computational pathology toolkit used for in multiplexed imaging analysis?

A computational pathology toolkit is used to analyze multiplexed immunofluorescence data, enabling spatial proteomics workflows for CODEX and Vectra platforms. It allows users to quantify marker expression and build spatial graphs representing cell interactions for downstream analysis.

Can I use this computational pathology toolkit with 160+ slide formats and HDF5?

Yes, this computational pathology toolkit supports over 160 slide formats for whole-slide image analysis and integrates directly with HDF5 for efficient data management. It handles multiplexed imaging, nucleus segmentation, and tissue graph construction without external format converters.

Does whole-slide image analysis support CODEX and Vectra multiplexed data?

Yes, whole-slide image analysis supports both CODEX and Vectra multiplexed data for spatial proteomics. The toolkit processes multiplexed immunofluorescence images to quantify marker expression and construct spatial graphs of cell interactions for machine learning model training.

What's the best way to build a spatial graph representing cell interactions from pathology slides?

The best way to build a spatial graph representing cell interactions is using a computational pathology toolkit that performs nucleus segmentation and tissue graph construction on whole-slide images. This workflow enables downstream machine learning model training on spatial relationships between cells.

How do I load a whole-slide image and generate tiles for processing?

To load a whole-slide image and generate tiles for processing, use the computational pathology toolkit's quick start functionality. It supports over 160 slide formats and creates tiled regions suitable for nucleus segmentation, marker quantification, and tissue graph construction.