What problem does it solve?
PrimeKG helps you search and connect multiscale biomedical entities (genes, drugs, diseases, phenotypes) to generate evidence-backed hypotheses for mechanisms and repurposing.
Core Features & Use Cases
- Entity Search (genes/drugs/diseases/phenotypes): Locate relevant nodes by name and optional type, then use the returned IDs for downstream graph queries.
- Neighborhood Retrieval: Pull direct associations for a chosen entity to inspect relationship types and sources.
- Disease Context Summaries: Compile associated genes, drugs, phenotypes, and related diseases for a disease name in one shot (useful for quick literature-style grounding).
- Use Cases: Drug discovery target finding, drug repurposing candidate exploration, phenotype-to-disease interpretation, and network pharmacology-style mapping from molecular targets to clinical outcomes.
Quick Start
Use primekg to summarize Alzheimer’s disease context and return associated genes, drugs, and phenotypes from the knowledge graph by asking your assistant to run the disease context workflow for the query name "Alzheimer's disease".