protein-mutation-analysis
CommunityAnalyze mutations of proteins; visualize effects.
Education & Research#visualization#analyze#uniprot#structure-prediction#esmfold#protein-mutations#mutation-explanation
AuthorPharMolix
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Protein mutations are critical to understanding gene function and disease; this skill retrieves protein data from UniProt, explains mutation effects with MutaPLM, predicts 3D structures with ESMFold, and visualizes results to support interpretation and decision making.
Core Features & Use Cases
- Retrieve: Get protein info (name, sequence, function) from UniProt for a given accession.
- Explain: Use MutaPLM to interpret the functional impact of a specified mutation (e.g., R248Q in TP53).
- Predict: Generate structural predictions with ESMFold for mutated variants.
- Visualize: Render 3D protein structures for analysis and communication.
- Use Case: Investigate a cancer-associated mutation to assess potential impact on structure and function.
Quick Start
Provide a UniProt ID and a mutation to run end-to-end analysis and visualization.
Dependency Matrix
Required Modules
None requiredComponents
references
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: protein-mutation-analysis Download link: https://github.com/PharMolix/OpenBioMed/archive/main.zip#protein-mutation-analysis Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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