protein-sequence-similarity-search
OfficialFind protein homologues via MMseqs2 or BLAST.
Education & Research#bioinformatics#blast#homology search#functional annotation#protein sequence#mmseqs2
Authorgoogle-deepmind
Version1.0.0
Installs0
System Documentation
What problem does it solve?
It identifies homologous protein sequences and helps infer likely protein functions from a user-provided amino-acid sequence, FASTA file, or related query.
Core Features & Use Cases
- Fast homologue search (MMseqs2 via ColabFold API): Runs a quick search by default and produces a ranked Markdown table of top hits.
- Comprehensive homologue search (EBI BLAST fallback): Falls back to slower BLAST when MMseqs2 fails (e.g., rate limits) or when the user explicitly requests BLAST or specific UniProt/structure databases.
- Functional interpretation and saved outputs: Interprets alignment metrics (Q-Cov, E-value, sequence identity) and writes results to local .md plus optional .json files for follow-on analysis.
Quick Start
Tell your agent: "Run a fast homologous protein search for this FASTA file and summarize the top hits and likely functions."
Dependency Matrix
Required Modules
scienceskillscommonpython-dotenv
Components
scripts
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: protein-sequence-similarity-search Download link: https://github.com/google-deepmind/science-skills/archive/main.zip#protein-sequence-similarity-search Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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