pysam-genomics

Community

Efficiently manipulate NGS data with pysam's Python interface.

Authorpradyumnasagar
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill simplifies the manipulation of NGS data by providing a Python interface to htslib, allowing users to read, modify, filter, and write BAM/CRAM/VCF files programmatically.

Core Features & Use Cases

  • NGS Data Manipulation: Read, modify, filter, and write NGS files like BAM/CRAM/VCF using pysam.
  • Python Integration: Seamlessly integrate with Python logic for advanced analysis.
  • Use Case: For example, users can extract variant or coverage data from a BAM file, build custom pipelines, or query regions without loading entire files.

Quick Start

Open the BAM file 'input.bam' and iterate through all alignments using pysam.

Dependency Matrix

Required Modules

pysamhtslib

Components

scripts

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: pysam-genomics
Download link: https://github.com/pradyumnasagar/open-research-skills/archive/main.zip#pysam-genomics

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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