query-kegg

Query KEGG REST API for pathway entries, gene lists, and gene records.

401|53|Updated Feb 26, 2026
One-click install
npx skills add https://github.com/Runchuan-BU/BioClaw --skill query-kegg
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: query-kegg
Source: https://github.com/Runchuan-BU/BioClaw/tree/main/.claude/skills/query-kegg
Command: npx skills add https://github.com/Runchuan-BU/BioClaw --skill query-kegg

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Provide fast, programmatic access to KEGG pathway, gene, and compound information so users can identify pathway memberships, retrieve pathway details, and obtain gene lists without manual browsing.

Core Features & Use Cases

  • Keyword pathway search: Find pathways matching a term (e.g., apoptosis, glycolysis) and return pathway IDs and names.
  • Pathway details and gene lists: Retrieve full pathway records and extract the genes linked to a pathway using KEGG REST API link/get endpoints.
  • Gene lookup and ID conversion: Fetch KEGG gene records and convert common gene identifiers for integration with downstream analyses.
  • Use Case: Quickly list human pathway genes for a metabolic pathway to perform overlap analysis with an experimental gene set.

Quick Start

Find KEGG pathways related to apoptosis in human and list the top five pathway IDs and names.

Frequently Asked Questions about query-kegg

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query KEGG pathways by keyword to find pathway IDs and names?

Query the KEGG REST API using the find operation with a keyword like apoptosis to retrieve matching pathway entries, returning pathway IDs and names for pathway-centric biological queries.

How do I get a list of genes linked to a specific KEGG pathway?

Retrieve pathway details and extract gene lists by using the KEGG REST API link and get endpoints with a pathway ID, returning gene records linked to that specific pathway.

Can I convert common gene identifiers to KEGG gene records for downstream analysis?

Fetch KEGG gene records using the REST API get operation to convert common gene identifiers, enabling integration with downstream annotation and pathway analysis tasks.

Does querying KEGG REST API require specific organism codes or KEGG IDs?

Querying the KEGG REST API requires network access to rest.kegg.jp and uses KEGG IDs or gene names as inputs, applying to listing organism-specific pathways for human and mouse.

What are the limitations of using the KEGG REST API for pathway analysis?

Limitations include the requirement for network access to rest.kegg.jp and the need to provide specific KEGG IDs or gene names as inputs for successful pathway and gene record retrieval.