rna-velocity-trajectory

What problem does it solve?

Infers directional cellular trajectories from scRNA-seq by modeling spliced/unspliced RNA to predict future cell states and map lineage relationships.

Core Features & Use Cases

• RNA velocity modeling with scVelo (steady-state and dynamical) to infer developmental trajectories.
• Uncertainty-aware inference via VeloVI and explicit topology modeling with Chronocell.
• CellRank integration for fate probabilities and terminal states, enabling robust lineage analysis.
• Supports upstream quantification of spliced/unspliced transcripts with velocyto, kb lamanno, or alevin-fry, and loading into AnnData layers.
• Use cases include predicting differentiation endpoints, identifying driver genes, validating lineage relationships, and analyzing transient populations.

Quick Start

Run a complete RNA velocity workflow on your scRNA-seq data to infer future cell states.