scientific-regulatory-genomics

Community

Regulatory genomics for variant interpretation.

Authornahisaho
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Regulatory genomics information is scattered across RegulomeDB, ReMap, and 4D Nucleome data sources; this pipeline unifies scoring, TF binding mapping, and 3D genome analysis for noncoding variant interpretation.

Core Features & Use Cases

  • RegulomeDB variant scoring to prioritize regulatory potential.
  • ReMap TF binding mapping to identify transcription factor occupancy in regions of interest.
  • 4D Nucleome based 3D genome structure analysis to contextualize regulatory variants.
  • End-to-end regulatory-variant integration pipeline that outputs consolidated results for downstream interpretation.

Quick Start

Invoke regulatory_variant_pipeline with a list of variants to compute RegulomeDB scores, map TF bindings, and retrieve 4D Nucleome interactions.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

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Please help me install this Skill:
Name: scientific-regulatory-genomics
Download link: https://github.com/nahisaho/satori/archive/main.zip#scientific-regulatory-genomics

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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