scikit-bio

Analyze biological sequences, alignments, and phylogenetic trees with Python.

Updated Mar 10, 2026
One-click install
npx skills add https://github.com/felixboehm/biochem-allergy --skill scikit-bio-felixboehm
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: scikit-bio
Source: https://github.com/felixboehm/biochem-allergy/tree/main/.claude/skills/scikit-bio
Command: npx skills add https://github.com/felixboehm/biochem-allergy --skill scikit-bio-felixboehm

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides a comprehensive Python library for biological data analysis, streamlining complex bioinformatics tasks from sequence manipulation to statistical ecology.

Core Features & Use Cases

  • Sequence Analysis: Process DNA, RNA, and protein sequences, perform alignments, and handle various biological file formats.
  • Phylogenetics & Diversity: Construct and analyze phylogenetic trees, calculate alpha and beta diversity metrics for ecological studies.
  • Statistical Ecology: Perform ordination (PCoA, CCA) and statistical tests (PERMANOVA) on biological data.
  • Use Case: Analyze microbiome data by reading a BIOM table, calculating diversity metrics, performing PCoA, and testing for significant differences between sample groups using PERMANOVA.

Quick Start

Use the scikit-bio skill to calculate the Shannon diversity for the provided count matrix.

Frequently Asked Questions about scikit-bio

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I calculate alpha and beta diversity metrics for microbiome data?

To calculate alpha and beta diversity metrics for microbiome data, you can use a Python bioinformatics toolkit to process biological count matrices and compute ecological diversity indices like Shannon diversity directly from your datasets.

What is the best way to perform PERMANOVA statistical tests on biological data?

The best way to perform PERMANOVA statistical tests on biological data is using a Python library for statistical ecology, which allows you to test for significant differences between biological sample groups after calculating diversity metrics.

Can I parse FASTA, FASTQ, and BIOM file formats in Python for sequence analysis?

Yes, you can parse FASTA, FASTQ, BIOM, and Newick file formats in Python for sequence analysis. A comprehensive bioinformatics toolkit supports reading, manipulating, and aligning DNA, RNA, and protein sequences from these biological file formats.

How do I run ordination methods like PCoA and CCA on ecological data?

To run ordination methods like PCoA and CCA on ecological data, use a Python statistical ecology toolkit to perform dimensionality reduction and visualize biological sample relationships following diversity metric calculations.

Does scikit-bio integrate with common data science libraries for phylogenetic tree construction?

Yes, scikit-bio integrates with common data science libraries for phylogenetic tree construction and analysis. It provides comprehensive Python functions to build, manipulate, and analyze phylogenetic trees alongside biological sequence data.