What problem does it solve?
This Skill helps researchers analyze complex single-cell and spatial omics data with probabilistic deep learning instead of ad hoc preprocessing and manual comparisons.
Core Features & Use Cases
- Batch Correction and Integration: Learn batch-invariant latent spaces for scRNA-seq, ATAC-seq, and multi-omic datasets.
- Annotation and Transfer Learning: Use semi-supervised models to label cells, map queries to references, and propagate labels across studies.
- Differential Expression and Deconvolution: Run Bayesian differential expression, accessibility testing, and spatial deconvolution with uncertainty estimates.
- Use Case: A researcher can train scVI on raw count matrices, then reuse the latent representation for clustering, visualization, and statistically grounded downstream analysis across batches or modalities.
Quick Start
Ask for the scvi-tools workflow to register raw count data, train the right model for my modality, and return latent embeddings, normalized outputs, and differential analysis results.