spectralbio-canonical-replay-and-portability-audit

Verify canonical TP53 replay boundaries and audit portability across BRCA2, TSC2, and CREBBP surfaces.

1|Updated Mar 21, 2026
One-click install
npx skills add https://github.com/DaviBonetto/SpectralBio --skill spectralbio-canonical-replay-and-portability-audit
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: spectralbio-canonical-replay-and-portability-audit
Source: https://github.com/DaviBonetto/SpectralBio/tree/main
Command: npx skills add https://github.com/DaviBonetto/SpectralBio --skill spectralbio-canonical-replay-and-portability-audit

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires numpy, pandas, matplotlib, requests, torch, transformers, scikit-learn, accelerate, and includes scripts (resource) and assets (resource) components.

What problem does it solve?

This Skill ensures the canonical TP53 replay path while auditing portability across BRCA2, TSC2, CREBBP, BRCA1, and MSH2 guardrails, enabling reproducible, reviewer-friendly validation.

Core Features & Use Cases

  • CPU-only replay with deterministic outputs and machine-checkable verifications.
  • Public route to verify a replay surface and inspect portability blocks across multiple targets.
  • Generates structured evidence surfaces for audit, provenance, and regeneration planning.

Quick Start

Execute a replay-audit workflow to verify TP53 and inspect portability surfaces for BRCA2, TSC2, and CREBBP.

Frequently Asked Questions about spectralbio-canonical-replay-and-portability-audit

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I audit TP53 replay portability across multiple genetic targets?

To audit TP53 replay portability, execute a deterministic replay-audit workflow that verifies the canonical replay boundary and inspects portability blocks across BRCA2, TSC2, and CREBBP surfaces. This generates machine-checkable summaries for reproducibility.

What is canonical replay boundary verification for biological targets?

Canonical replay boundary verification identifies and validates the exact TP53 regeneration path while auditing its portability across guardrail targets like BRCA1, MSH2, and CREBBP. It produces structured evidence surfaces for provenance and reviewer-friendly audit validation.

Can I run a deterministic replay audit in a CPU-only offline environment?

Yes, you can run deterministic replay audits in a CPU-only offline environment. The process is specifically designed for CPU-only replay, producing bounded evidence and machine-checkable verifications without requiring GPU acceleration.

Do I need a SKILL.md frontmatter file to perform a replay portability audit?

Yes, you need a SKILL.md frontmatter at the repository root with a defined name and description to perform a replay portability audit. The environment may also reference optional directories like scripts and assets to execute deterministic tasks.

How does portability auditing work across BRCA2, TSC2, and CREBBP surfaces?

Portability auditing works by inspecting replay surfaces across BRCA2, TSC2, and CREBBP to ensure the canonical TP53 path holds. It generates structured evidence for audit, provenance tracking, and regeneration planning across these genetic guardrails.