tooluniverse-protein-structure-retrieval

Retrieve protein structures from RCSB PDB, PDBe, and AlphaFold with disambiguation and quality assessment.

2|Updated May 7, 2026
One-click install
npx skills add https://github.com/Teng-bio/codex-skills-hub --skill tooluniverse-protein-structure-retrieval-teng-bio
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: tooluniverse-protein-structure-retrieval
Source: https://github.com/Teng-bio/codex-skills-hub/tree/main/skills/global/tooluniverse-protein-structure-retrieval
Command: npx skills add https://github.com/Teng-bio/codex-skills-hub --skill tooluniverse-protein-structure-retrieval-teng-bio

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires RCsbPDB, PDBe, AlphaFold, and includes scripts (resource) and references (resource) and assets (resource) components.

What problem does it solve?

This Skill facilitates the retrieval of protein structure data, including disambiguation, quality assessment, and detailed profiles. It is designed to support users in acquiring precise 3D models, crystallographic data, and related metadata.

Core Features & Use Cases

  • Comprehensive Retrieval: Access protein structures from RCSB PDB, PDBe, and AlphaFold with precise disambiguation and quality metrics.
  • Structure Reports: Generate detailed reports with experimental data, ligand information, and download links.
  • Use Case: Users requiring 3D protein models, such as in drug design or structural biology, can employ this Skill to retrieve structures with high-resolution and accuracy.

Quick Start

Retrieve the protein structure for insulin by executing the command: retrieve_structure --protein "insulin"

Frequently Asked Questions about tooluniverse-protein-structure-retrieval

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve protein structure data from RCSB PDB, PDBe, and AlphaFold?

You retrieve protein structure data by querying multiple databases with automated disambiguation. This Skill fetches comprehensive 3D models, crystallographic data, and quality metrics from RCSB PDB, PDBe, and AlphaFold APIs simultaneously.

What is protein structure disambiguation and why do I need it for drug design?

Protein structure disambiguation resolves ambiguous protein identifiers to ensure accurate retrieval of 3D models. It prevents fetching incorrect structures, which is critical for drug design and structural biology applications requiring high-resolution data.

Can I get quality assessment metrics for AlphaFold predicted protein models?

Yes, you can get quality assessment metrics for AlphaFold predicted protein models. The Skill retrieves comprehensive metadata and quality indicators alongside the structural data to help evaluate model accuracy for downstream analysis.

Does this protein structure retrieval tool require direct API access to PDB and PDBe?

Yes, this protein structure retrieval tool requires access to RCSB PDB and PDBe APIs. You need valid API connectivity to fetch experimental data, ligand information, and download links for your protein structure reports.

What's the best way to get a comprehensive structure report with ligand information and download links?

The best way to get a comprehensive structure report is to use the retrieval command with your target protein name. The Skill generates detailed reports containing experimental data, ligand information, and direct download links from multiple databases.

Are there limitations when retrieving crystallographic data versus predicted structural biology models?

Retrieving crystallographic data depends on available experimental entries in RCSB PDB and PDBe, while AlphaFold provides predicted models for proteins lacking experimental structures. The Skill includes quality assessment to help you evaluate the reliability of both data types.

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