ucsc-genome-browser

To retrieve DNA sequences for a specific genomic region from the UCSC Genome Browser, you can programmatically query the UCSC REST API using chromosome coordinates. This enables fetching exact DNA sequences across over 100 supported genome assemblies without manual web browsing.

Yes, you can query gene annotations and conservation scores using the UCSC REST API. The skill supports retrieving gene models from the refGene track and obtaining per-base conservation scores for specified genomic loci across multiple assemblies.

Over 100 genome assemblies are supported for fetching genomic sequences and annotations, including human, mouse, and fly. This allows researchers to query metadata, chromosome sizes, and available tracks for a wide range of organisms programmatically.

To get available tracks and chromosome sizes for a given genome assembly, you can use programmatic access to query the UCSC REST API. This metadata discovery feature lists all annotation tracks and chromosome lengths for the specified assembly.

You need Python libraries like requests to access UCSC Genome Browser data programmatically via the REST API. Matplotlib is also included as a dependency, supporting downstream visualization of the retrieved genomic sequences and conservation scores.