Upstream Processing Skills Index

Official

Orchestrate upstream omics data preprocessing.

Authoraristoteleo
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Upstream Processing Skills Index centralizes and standardizes the initial data preparation workflows for single-cell and spatial omics, enabling teams to identify, assemble, and execute technology-specific preprocessing pipelines from raw sequencing data to analysis-ready matrices.

Core Features & Use Cases

  • Unified catalog of upstream pipelines (OpenST, nf-core) for raw data to counts.
  • Platform-agnostic workflows: covers barcode preprocessing, transcriptome alignment, spatial registration, segmentation, and 3D reconstruction.
  • End-to-end readiness: moves data from raw reads to analysis-ready matrices and downstream analysis readiness.
  • Real-world scenario: a team processes a Visium-like dataset with OpenST to obtain spatially-resolved gene counts ready for downstream clustering.

Quick Start

Load the desired upstream skill (OpenST or nf-core) and run its end-to-end workflow from raw data to count matrices.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: Upstream Processing Skills Index
Download link: https://github.com/aristoteleo/PantheonOS/archive/main.zip#upstream-processing-skills-index

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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