vasopressor-equivalents

Compute norepinephrine-equivalent dose from concurrent vasopressors with time-interval aggregation.

40|17|Updated Oct 27, 2025

Search Tags:#vasopressor #norepinephrine #hemodynamics #critical-care #dose-equivalence #time-weighted #shock

Ready to run

npx skills add https://github.com/hannesill/m4 --skill vasopressor-equivalents

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: vasopressor-equivalents
Source: https://github.com/hannesill/m4/tree/main/src/m4/skills/clinical/vasopressor-equivalents
Command: npx skills add https://github.com/hannesill/m4 --skill vasopressor-equivalents

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) components.

What problem does it solve?

This tool computes norepinephrine-equivalent dose to enable cross-agent comparisons of vasopressor exposure in critical care and research settings.

Core Features & Use Cases

Equivalence calculation: combines norepinephrine, epinephrine, dopamine, phenylephrine, and vasopressin with standard conversion factors to produce a single norepinephrine-equivalent dose.
Time-aware analysis: respects active dosing intervals (starttime/endtime) to support time-weighted assessments and cohort analyses.
Research-ready outputs: supports integration into cohort studies for shock severity staging and vasopressor weaning research; includes explicit notes on handling weight estimation and unit conversions.
Use Case: If a patient receives norepinephrine and vasopressin concurrently, the tool yields a combined norepinephrine-equivalent dose for downstream analytics.

Quick Start

Automatically compute norepinephrine-equivalent dose from concurrent vasopressor doses to enable cross-agent comparisons.

Frequently Asked Questions about vasopressor-equivalents

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I calculate norepinephrine-equivalent dose from concurrent vasopressors?▼

To calculate norepinephrine-equivalent dose (NED) from concurrent vasopressors, apply standard weight-based conversion factors to combine norepinephrine, epinephrine, dopamine, phenylephrine, and vasopressin into a single comparative dose.

What is a norepinephrine-equivalent dose and when is it needed?▼

Norepinephrine-equivalent dose is a standardized metric enabling cross-agent comparisons of vasopressor exposure. It is needed for critical care research workflows performing cohort analysis and shock severity staging across patients receiving different agents.

How do you handle vasopressin units when computing time-weighted vasopressor exposure?▼

Handling vasopressin units requires specific unit conversions within the equivalence calculation. The process respects active dosing intervals defined by starttime and endtime to support accurate time-weighted assessments and per-stay aggregation.

Can I use vasopressor dose equivalence calculations for time-based cohort analysis in critical care datasets?▼

Yes, you can use vasopressor dose equivalence calculations for time-based cohort analysis in critical care datasets. The computation aggregates active dosing intervals and applies weight-based conversions to yield per-stay results suitable for research.

Does norepinephrine-equivalent dose calculation support concurrent vasopressin and norepinephrine infusions?▼

Norepinephrine-equivalent dose calculation does support concurrent vasopressin and norepinephrine infusions. It combines these agents with standard conversion factors to yield a combined equivalent dose for downstream analytics and weaning research.

What are the limitations of using norepinephrine-equivalent dose for shock severity staging?▼

Limitations of norepinephrine-equivalent dose for shock severity staging include the need for explicit weight estimation and careful unit conversions. The metric provides a standardized comparison but requires accurate active dosing interval data to avoid errors.