OmicsClaw
Local-first multi-omics analysis across eight research domains
All Skills in This Repository (56)
Pure Emerald Level IndicatorsLiterature Parsing Skill
Parse scientific literature to extract GEO dataset metadata and download associated data.
orchestrator
Route natural language queries to omics analysis skills across multiple domains.
metabolomics-annotation
Annotate metabolomics features by matching MS2 spectra against SIRIUS, GNPS, and MetFrag databases.
metabolomics-normalization
Normalize metabolomics data using median, quantile, total-ion-count, PQN, and log2 transformations.
metabolomics-de
Perform univariate and multivariate statistical analysis on metabolomics data to identify biomarkers.
metabolomics-quantification
Impute missing values and normalize metabolomics feature data.
metabolomics-statistics
Perform univariate statistical tests and FDR correction on metabolomics data.
metabolomics-xcms-preprocessing
Preprocess LC-MS/GC-MS metabolomics data with XCMS3 peak detection and alignment.
metabolomics-peak-detection
Detect metabolite peaks from LC-MS data using XCMS, MZmine 3 or MS-DIAL and extract features for downstream analysis.
metabolomics-pathway-enrichment
Perform metabolomics pathway enrichment with hypergeometric tests and FDR correction.
sc-grn
Infers gene regulatory networks from single-cell expression data using pySCENIC or correlation-based fallback.
sc-batch-integration
Integrate multi-sample single-cell RNA sequencing data with Harmony, scVI, Seurat CCA/RPCA, BBKNN, and fastMNN.
Frequently Asked Questions
FAQPage SchemaHow to install OmicsClaw?โผ
Run `npx skills add TianGzlab/OmicsClaw --all -g -y` in your terminal to install all skills in this suite globally.
What omics data types does OmicsClaw support?โผ
It covers eight domains: spatial transcriptomics, single-cell omics, genomics, proteomics, metabolomics, bulk RNA-seq, orchestration, and literature parsing, with 95 registered analysis skills.
Does OmicsClaw keep my data private?โผ
Yes. All processing is local-first, so raw matrices never leave your machine; remote Linux execution over SSH is optional for large server-side data.
Can I run analyses without writing code?โผ
Yes. You describe the analysis in plain language and the orchestrator routes it to the right skill, which runs reproducible scripts and returns figures, tables, and reports.
Does OmicsClaw work with Claude Code and other agents?โผ
Yes. Every skill follows the standard SKILL.md format and runs through a unified CLI (`oc run <skill>`), so it works in Claude Code, Cursor, and other compatible agent environments.
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