tt-bio

Run `npx skills add moritztng/tt-bio --all -g -y` in your terminal to install all skills in this suite globally.

It runs protein structure prediction, binder design, and binding affinity models such as Boltz-2, ESMFold2, Protenix, and OpenFold3 on Tenstorrent Blackhole and Wormhole hardware.

Yes. The Boltz-2 CPU and GPU path and the command-line interface work on a standard host, while the other models require a Tenstorrent card.

Every model is validated against its official reference implementation on the same input and reproduces results within that reference's own run-to-run noise.

Yes. It supports single-card and multi-card configurations like a 4-card QuietBox or 32-card Galaxy server, and multiple machines can be combined into one prediction run.