alterlab-gene-db

Batch lookup of gene annotations is performed by querying NCBI Gene data via E-utilities and the Datasets API to fetch symbols, IDs, GO terms, RefSeqs, and locations across species. The workflow supports large gene lists with robust error handling.

NCBI E-utilities and Datasets API retrieval returns comprehensive gene metadata including symbols, IDs, GO terms, RefSeqs, chromosomal locations, phenotypes, and cross-references for downstream analyses. Data is fetched by querying gene symbols or IDs.

An NCBI API key is optional for performing gene annotation lookups via E-utilities and the Datasets API. The workflow supports optional API keys alongside robust error handling to retrieve standardized gene metadata without a mandatory key requirement.

The best way to compile standardized gene panels is querying NCBI Gene data by symbol or ID to fetch comprehensive annotations in one step. Researchers can cross-reference NCBI Gene and Datasets resources to retrieve GO terms, RefSeqs, and phenotypes.

Fetching chromosomal locations and cross-references for a list of gene symbols is fully supported. The workflow queries NCBI Gene and Datasets resources to return comprehensive metadata including locations, RefSeqs, and cross-references across multiple organisms.