alterlab-neuropixels

Community

End-to-end Neuropixels data analysis workflow

AuthorAlterLab-IEU
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Neuropixels Data Analysis for end-to-end processing of Neuropixels data, from raw recordings to curated neuronal units across NP1.0/NP2.0, enabling researchers to generate publication-ready results with AI-assisted curation.

Core Features & Use Cases

  • Load and preprocess data from SpikeGLX/Open Ephys/NWB formats.
  • Apply motion/drift correction, spike sorting (Kilosort4, SpykingCircus, Mountainsort5), and quality metrics per Allen/IBL criteria.
  • AI-assisted curation with Claude Vision for rapid, visual quality assessments.
  • Export results to Phy, NWB, and generate publication-quality figures and reports.
  • Use cases include electrophysiology studies, neural decoding pipelines, and cross-protocol data curation.

Quick Start

Run the Neuropixels pipeline on your dataset by calling the neuropixels_pipeline.py script with the path to your data and an output directory.

Dependency Matrix

Required Modules

spikeinterfacepandasnumpymatplotlibprobeinterface

Components

scriptsreferencesassets

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: alterlab-neuropixels
Download link: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/archive/main.zip#alterlab-neuropixels

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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