antibody-structure-prediction-tfold

Predict antibody and nanobody structures from sequences using tfold-based models.

1.1k|132|Updated Apr 13, 2023
One-click install
npx skills add https://github.com/PharMolix/OpenBioMed --skill antibody-structure-prediction-tfold
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: antibody-structure-prediction-tfold
Source: https://github.com/PharMolix/OpenBioMed/tree/main/skills/antibody-structure-prediction-tfold
Command: npx skills add https://github.com/PharMolix/OpenBioMed --skill antibody-structure-prediction-tfold

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Predict antibody and nanobody structures from sequence data.

Core Features & Use Cases

  • Antibody and nanobody structure prediction from heavy/light chain sequences.
  • Antigen-antibody complex structure prediction from paired sequences.

Quick Start

Provide heavy and light chain sequences to generate the predicted antibody structure.

Frequently Asked Questions about antibody-structure-prediction-tfold

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I predict an antibody structure from sequence data?

To predict an antibody structure from sequence data, you provide the heavy and light chain sequences as input to generate the predicted 3D structure using the tfold-based local prediction model.

Can I predict nanobody structures using this tool?

Yes, you can predict nanobody structures by providing the specific sequence data to the local tfold-based prediction environment, which supports both standard antibodies and nanobodies.

How do I predict an antigen-antibody complex structure?

You can predict an antigen-antibody complex structure by providing paired sequences of the antibody and antigen to the local tfold model, which will generate the predicted complex structure.

Do I need a local GPU to run antibody structure prediction with tfold?

Yes, you need a local GPU because the antibody structure prediction process runs in a local environment and requires local GPU hardware along with the necessary dependencies and models.

What is the best way to model an antigen-antibody complex locally?

The best way to model an antigen-antibody complex locally is to use a tfold-based model with paired sequences, which runs directly on your local GPU to generate the complex structure.