bio-de-edger-basics

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Robust edgeR-based differential expression analysis.

Authorya-way
Version1.0.0
Installs0

System Documentation

What problem does it solve?

edgeR-based differential expression analysis for RNA-seq count data using the quasi-likelihood framework to identify condition-associated gene expression changes.

Core Features & Use Cases

  • DGEList construction from count matrices with group annotations
  • Filtering low-expression genes
  • Normalization using TMM
  • Design matrices for complex experiments
  • Dispersion estimation and GLM quasi-likelihood testing
  • Extraction of DE results with FDR control
  • Use case: identify DE genes between treated vs control, adjusting for batch

Quick Start

Run edgeR on your count matrix to compare two groups and retrieve the top DE genes with FDR control

Dependency Matrix

Required Modules

None required

Components

Standard package

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Please help me install this Skill:
Name: bio-de-edger-basics
Download link: https://github.com/ya-way/cytoclaw-skills/archive/main.zip#bio-de-edger-basics

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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