bio-nextflow-manager

Execute nf-core bioinformatics pipelines for omics data analysis.

114|13|Updated Jan 17, 2026
One-click install
npx skills add https://github.com/frumu-ai/tandem --skill bio-nextflow-manager
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: bio-nextflow-manager
Source: https://github.com/frumu-ai/tandem/tree/main/src-tauri/resources/skill-templates/bio-nextflow-manager
Command: npx skills add https://github.com/frumu-ai/tandem --skill bio-nextflow-manager

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill automates the deployment and execution of complex bioinformatics pipelines for analyzing omics sequencing data, making advanced analysis accessible to researchers without deep bioinformatics expertise.

Core Features & Use Cases

  • Pipeline Execution: Runs nf-core pipelines (rnaseq, sarek, atacseq) for RNA-seq, WGS/WES, and ATAC-seq data.
  • Data Acquisition: Facilitates downloading public datasets from GEO/SRA.
  • Environment Management: Checks and ensures necessary software (Python, Bash, Docker, Nextflow, Java) is correctly configured.
  • Use Case: A biologist needs to analyze RNA sequencing data from a public GEO dataset to understand gene expression. This Skill can download the data, set up the environment, run the rnaseq pipeline, and verify the results.

Quick Start

Use the bio-nextflow-manager skill to run the rnaseq pipeline on the data located at /path/to/fastq.

Frequently Asked Questions about bio-nextflow-manager

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I run nf-core RNA-seq pipelines on local FASTQ files?

To run nf-core pipelines on local FASTQ files, the Skill executes the rnaseq pipeline directly by pointing to your local data path after verifying that Nextflow, Java, and Docker are configured.

Can I download public GEO or SRA datasets for variant calling automatically?

Yes, you can download public datasets for variant calling automatically. The Skill acquires public omics data from GEO and SRA accessions to use as input for WGS and WES analysis via the sarek pipeline.

What software environment is required to execute Nextflow bioinformatics pipelines?

Executing Nextflow bioinformatics pipelines requires Python, Bash, Docker, Nextflow, and Java. The Skill checks and ensures this entire environment is correctly configured before running any omics data analysis.

Does this approach support ATAC-seq data for chromatin accessibility studies?

Yes, this approach supports ATAC-seq data for chromatin accessibility studies. The Skill executes the nf-core atacseq pipeline to process your sequencing data and generate the required accessibility results.

What's the best way to analyze RNA sequencing data without deep bioinformatics expertise?

The best way to analyze RNA sequencing data without deep bioinformatics expertise is using automated deployment. The Skill handles environment setup, data acquisition, and pipeline execution for gene expression analysis end-to-end.

Why does my nf-core pipeline execution fail before processing sequencing data?

Pipeline execution fails before processing sequencing data when environment dependencies are missing. The Skill prevents this by checking for required software like Python, Docker, and Java before attempting to run any analysis.