bio-reads-qc-mapping

Ingest, QC, and map sequencing reads to generate coverage metrics.

7|1|Updated Feb 2, 2026
One-click install
npx skills add https://github.com/fmschulz/omics-skills --skill bio-reads-qc-mapping
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: bio-reads-qc-mapping
Source: https://github.com/fmschulz/omics-skills/tree/main/skills/bio-reads-qc-mapping
Command: npx skills add https://github.com/fmschulz/omics-skills --skill bio-reads-qc-mapping

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Ingest, QC, and map reads with reproducible outputs. Use for raw read processing and coverage stats.

Core Features & Use Cases

  • Ingest and validate sample sheets and input reads
  • Run QC/trimming and map reads to a reference to generate coverage statistics
  • Use in small to large sequencing projects, including Illumina short reads and long-read data, with transparent logging and reproducible results

Quick Start

Process raw sequencing reads by performing QC and mapping to a reference to generate basic coverage reports.

Frequently Asked Questions about bio-reads-qc-mapping

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I run QC and map sequencing reads to generate coverage metrics?

To run QC and map sequencing reads, ingest raw reads with a sample sheet, perform trimming, and map them to a reference to generate reproducible coverage statistics and logs.

Can I use this workflow for both Illumina short reads and Nanopore long reads?

Yes, this workflow supports both Illumina short reads and long-read data from Nanopore and PacBio, generating transparent logging and reproducible coverage results across diverse sequencing platforms.

What is the best way to ensure reproducible quality control for raw sequencing data?

The best way to ensure reproducible quality control is to specify input validation, run QC and trimming steps, and map reads to a reference, ensuring traceable results and logs for quality gates.

Do I need a reference genome to calculate coverage statistics from my reads?

Yes, you need an optional reference to map your reads against, as the workflow maps sequencing reads to a reference to generate basic coverage reports and validate samples.

Why does my read mapping workflow lack traceable results for quality gates?

Your read mapping workflow lacks traceability if it skips input validation and transparent logging, which are required to ensure traceable results and logs for quality gates in sequencing projects.