biomni

Plan and execute autonomous biomedical research tasks across multi-omics and clinical data.

75|7|Updated Feb 14, 2026
One-click install
npx skills add https://github.com/jiaxiaojunQAQ/SkillJect --skill biomni-jiaxiaojunqaq
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: biomni
Source: https://github.com/jiaxiaojunQAQ/SkillJect/tree/main/data/skills_sample/biomni
Command: npx skills add https://github.com/jiaxiaojunQAQ/SkillJect --skill biomni-jiaxiaojunqaq

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) components.

What problem does it solve?

Biomni provides an autonomous framework that orchestrates data access, reasoning, and code execution to perform complex biomedical research tasks without manual prompt engineering. It integrates a local data lake, multiple LLM providers, and optional MCP servers to enable end-to-end analysis across genomics, proteomics, clinical data, and literature.

Core Features & Use Cases

  • Autonomous task decomposition and execution for CRISPR design, scRNA-seq analysis, GWAS interpretation, and drug discovery workflows.
  • Integrated data access and knowledge retrieval from biomedical databases and literature with code generation and execution for reproducible results.
  • Extensible with external tools via MCP servers and a configurable execution environment for safe, reproducible analyses.

Quick Start

Initialize Biomni with your data lake path and an LLM, then run a representative biomedical task to see autonomous execution.

Frequently Asked Questions about biomni

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I automate scRNA-seq analysis and CRISPR design workflows without manual prompt engineering?

Autonomous biomedical research agents orchestrate data access, reasoning, and code execution to handle scRNA-seq analysis and CRISPR design end-to-end. By integrating LLMs with a local data lake, these agents decompose complex research tasks into executable code automatically.

Can I use an LLM to interpret GWAS results and run drug discovery tasks across multi-omics data?

LLM-driven autonomous agents interpret GWAS results and perform drug discovery by integrating multi-omics and clinical data. They retrieve knowledge from biomedical databases, generate reproducible analysis code, and execute it within a configurable environment.

Do I need a local data lake to run autonomous biomedical research pipelines?

Yes, a local data lake is required to enable autonomous biomedical research pipelines. The framework loads default configurations and API keys to access LLM providers, ensuring reproducible execution across genomics, proteomics, and clinical data.

What is the best way to generate reproducible analysis code for clinical and multi-omics data?

Generating reproducible analysis code for multi-omics data is best handled by autonomous research frameworks. They integrate data lakes with LLMs to generate and execute runnable code with provenance, ensuring clinical data analysis remains safe and reproducible.

Does biomni work with MCP servers for extending biomedical research tasks?

Biomni works with optional MCP servers to extend biomedical research capabilities with external tools. This integration allows the autonomous agent to access additional knowledge retrieval sources and perform specialized tasks within its execution environment.

When should I not use an autonomous agent for biomedical data analysis?

Autonomous agents should not be used for biomedical data analysis when a local data lake is unavailable or when LLM provider access is restricted. Without these prerequisites, the framework cannot load configurations or generate executable, reproducible research pipelines.