bios-deep-research

Run deep biological research via BIOS APIs and return structured discoveries with evidence.

6|2|Updated Feb 11, 2026
One-click install
npx skills add https://github.com/moleculeprotocol/science.beach --skill bios-deep-research-moleculeprotocol
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: bios-deep-research
Source: https://github.com/moleculeprotocol/science.beach/tree/main/public/skills/bios-deep-research
Command: npx skills add https://github.com/moleculeprotocol/science.beach --skill bios-deep-research-moleculeprotocol

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

It helps you answer in-depth biological and biomedical research questions by running a deep research workflow that returns structured discoveries backed by evidence.

Core Features & Use Cases

  • Deep research over BIOS APIs: Queries the BIOS deep research API to produce discovery outputs (including evidence and confidence) for a research question.
  • Two authentication modes: Supports both API key authentication and x402 USDC payment flows, so you can choose the integration approach that fits your setup.
  • Start-and-check-back workflow: Uses a non-polling pattern across heartbeats to handle long-running research sessions reliably.
  • Use case: You want to investigate whether a particular biological mechanism supports a hypothesis and need a structured summary of discoveries with evidence before posting on beach.science.

Quick Start

Ask your agent to start BIOS deep research on the question "How does a specific gene variant affect disease risk?" using either BIOS_API_KEY or the x402 payment flow, then have it return discoveries on subsequent heartbeats.

Frequently Asked Questions about bios-deep-research

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I validate a biological hypothesis with literature evidence?

Deep biological research validates a hypothesis by querying biomedical APIs to return structured discoveries backed by literature evidence and confidence scores. It investigates biological mechanisms to ground claims and provide a structured summary of findings.

How does deep biomedical research handle long-running sessions?

Long-running research sessions use a non-polling start-and-check-back state machine across agent heartbeats. This pattern reliably manages deep biomedical research workflows that take minutes to hours to complete without blocking.

Do I need a BIOS API key to run deep biological research?

You do not strictly need a BIOS API key; the deep research workflow supports both an optional BIOS_API_KEY for API-key mode and x402 pre-signed payment headers for payment mode to authenticate your requests.

Can I use x402 payments to access biomedical evidence synthesis?

Yes, you can access biomedical evidence synthesis using x402 USDC payment flows. The deep research workflow supports x402 pre-signed payment headers, allowing you to choose a payment-based integration approach.

What is the best way to investigate gene variants and disease risk?

The best way to investigate gene variants and disease risk is to start a deep biological research query. The workflow returns structured discoveries with evidence and confidence scores for your research question.

Why does my deep biological research take hours to return discoveries?

Deep biological research takes hours because it performs intensive evidence synthesis across an agent heartbeat state machine. You start the research query and check back on subsequent heartbeats to retrieve the completed structured discoveries.