Run BLAST searches for DNA, RNA, or protein sequences in BioClaw.
npx skills add https://github.com/Runchuan-BU/BioClaw --skill blast-search-runchuan-bu
Please help me install this Agent Skill. Skill: blast-search Source: https://github.com/Runchuan-BU/BioClaw/tree/main/.claude/skills/blast-search Command: npx skills add https://github.com/Runchuan-BU/BioClaw --skill blast-search-runchuan-bu
BLAST-based sequence similarity is essential for identifying homology and functional clues; this skill provides an integrated, containerized BLAST workflow to run local or remote searches from BioClaw.
Provide a DNA or protein sequence and specify whether you want nucleotide or protein BLAST.
High-intent search queries and answers about installing and using this skill.
To run a BLAST search, provide a DNA or protein sequence and specify the desired program type, such as blastn or blastp. The tool identifies sequence similarity by querying local or remote NCBI databases and returns top hits with identity and e-value information.
Yes, you can use blastn, blastp, blastx, and tblastn against NCBI nucleotide and protein databases. The tool supports both local database queries inside the container and remote NCBI BLAST searches for identifying sequence homology.
The best way to get e-value and identity information is to run your sequence search through this integrated workflow. It formats the top hits with identities, e-values, and brief annotations, providing the essential metrics needed to evaluate sequence similarity.
Yes, BLAST sequence search supports downstream analyses such as multiple sequence alignment and phylogeny. After identifying sequence similarity and retrieving top hits, you can proceed with these follow-up analyses to further evaluate evolutionary relationships.
A containerized BLAST workflow provides an integrated environment to run local or remote sequence similarity searches without manual database setup. It standardizes the process of querying nucleotide and protein sequences, ensuring consistent results for homology identification.
You do not need to prepare local databases before running BLAST. The tool supports remote NCBI BLAST searches against nucleotide and protein databases by default, while also offering the option to query user-provided local databases within the container.
RamanEbrahimiIntegrate Biopython for sequence manipulation, file parsing, and BLAST automation.
JosephWoodallInfer evolutionary relationships from nucleotide or protein sequences using MAFFT, IQ-TREE 2, and ETE3.
jasrajtulsiUnify bioinformatics database queries and identifier mapping in Python workflows.
yf8578Performs nucleotide and protein sequence similarity searches via NCBI BLAST+ locally or remotely.
