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cancer-curator

Curate cancer entries with genetic drivers, pathophysiology, and ontology bindings.

50|9|Updated Dec 4, 2025
Search Tags:#evidence#pathophysiology#cancer-curation#oncogenes#histopathology#targeted-therapy#ontologies
One-click install
npx skills add https://github.com/monarch-initiative/dismech --skill cancer-curator
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: cancer-curator
Source: https://github.com/monarch-initiative/dismech/tree/main/.claude/skills/cancer-curator
Command: npx skills add https://github.com/monarch-initiative/dismech --skill cancer-curator

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Cancer data curation in dismech requires structured, standards-compliant entries and traceable evidence; this skill streamlines the creation and enhancement of cancer-related entries with proper pathophysiology, histopathology, therapy links, and genetic drivers.

Core Features & Use Cases

  • Curate cancer and neoplastic disease entries with atomic pathophysiology, causal chains, and ontology bindings (MONDO/HP/NCIT/GO).
  • Add targeted therapies, biomarkers, and genetic drivers, including fusions and oncogene addiction, with references.
  • Improve data quality and consistency by enforcing evidence-backed claims and reproducible curation workflows.

Quick Start

Use the cancer-curator skill to create or update a cancer/neoplasm entry with genetic drivers, pathophysiology, histopathology, and treatment associations.

Frequently Asked Questions about cancer-curator

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I curate cancer disease entries with ontology bindings and evidence validation?▼

Cancer entry curation involves organizing atomic disease mechanisms, histopathology, and therapeutic guidance with ontology bindings to MONDO, HP, NCIT, and GO. The skill enforces structured data and validates claims against external ontologies and literature references to ensure reproducibility.

What is atomic pathophysiology curation for neoplastic diseases?▼

Atomic pathophysiology curation breaks cancer mechanisms into discrete causal chains linked to genetic drivers like oncogenes and tumor suppressors. It ensures each mechanistic step is an evidence-backed claim with traceable references to external literature and ontology terms.

How do I add targeted therapies and genetic drivers to a cancer knowledge base?▼

You add targeted therapies, biomarkers, and genetic drivers including fusions and oncogene addiction by creating structured entries with ontology bindings. Each therapeutic association requires evidence-backed claims validated against external literature references.

Can I use this curation approach for histopathology findings and tumor suppressor genes?▼

Yes, the curation workflow supports histopathology findings and genetic drivers including tumor suppressors, oncogenes, and fusions. Entries are structured with pathophysiology causal chains and therapeutic associations, all validated against external ontologies.

What's the best way to ensure evidence-backed claims in cancer data curation?▼

The best way to ensure evidence-backed claims is enforcing structured data validation against external ontologies and literature references during curation. This approach standardizes genetic drivers, pathophysiology, and targeted therapy entries for consistent data quality.

Does cancer curation require ontology bindings for pathophysiology and therapy data?▼

Cancer curation requires ontology bindings to MONDO, HP, NCIT, and GO for pathophysiology, histopathology, and therapeutic guidance. These bindings enforce standards-compliant entries with traceable evidence for genetic drivers and treatment associations.

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