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clinpgx-database

Query the ClinPGx pharmacogenomics database for gene-drug interactions and CPIC guidelines.

Updated Mar 10, 2026
Search Tags:#genetics#pharmacogenomics#clinpgx#precision medicine#drug metabolism#CPIC guidelines
One-click install
npx skills add https://github.com/felixboehm/biochem-allergy --skill clinpgx-database-felixboehm
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/felixboehm/biochem-allergy/tree/main/.claude/skills/clinpgx-database
Command: npx skills add https://github.com/felixboehm/biochem-allergy --skill clinpgx-database-felixboehm

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides access to comprehensive pharmacogenomic data, enabling precise, genotype-guided medication decisions and improving patient outcomes.

Core Features & Use Cases

  • Gene-Drug Interaction Queries: Understand how genetic variations affect drug response.
  • CPIC Guideline Access: Retrieve evidence-based recommendations for clinical practice.
  • Allele and Variant Information: Get detailed data on genetic variations and their functional impact.
  • Use Case: A clinician can use this Skill to quickly check if a patient's CYP2C19 genotype necessitates an alternative to clopidogrel, referencing CPIC guidelines for the recommendation.

Quick Start

Query the ClinPGx API for gene-drug pair information for CYP2D6 and codeine.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve CPIC guidelines for genotype-guided dosing using pharmacogenomics data?▼

To retrieve CPIC guidelines for genotype-guided dosing, you can query the ClinPGx database for specific gene-drug pairs, enabling evidence-based clinical recommendations. This integrates data from CPIC, PharmGKB, and PharmCAT.

What is the best way to check gene-drug interactions and allele functions for adverse drug reaction risk assessment?▼

The best way to check gene-drug interactions and allele functions for risk assessment is querying a pharmacogenomics database. This approach provides detailed data on genetic variations and their functional impact on drug metabolism.

Can I use Python scripts with pandas to access pharmacogenomics data for precision medicine?▼

Yes, you can use Python scripts utilizing the requests and pandas libraries to programmatically access pharmacogenomics data. This setup enables efficient queries for gene-drug interactions and clinical decision support.

Does the ClinPGx database integrate PharmGKB and PharmCAT data for clinical decision support?▼

Yes, the ClinPGx database integrates comprehensive data from PharmGKB, PharmCAT, and CPIC. This integration supports clinical decision making by providing genotype-guided dosing recommendations and adverse drug reaction risk assessments.

How do I find alternative medication recommendations when a patient's CYP2D6 genotype affects codeine metabolism?▼

To find alternative medication recommendations for CYP2D6 and codeine, query the pharmacogenomics database for the specific gene-drug pair. The API returns CPIC guidelines detailing necessary dosing adjustments or alternative therapies.

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