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clinpgx-database

Query ClinPGx pharmacogenomics data for gene–drug interactions and CPIC guidelines.

18|1|Updated Dec 27, 2025
Search Tags:#pathways#drug-labels#pharmacogenomics#gene-drug#cpic#allele#clinpgx
One-click install
npx skills add https://github.com/LogauaEngstrom/claude-scientific-skills --skill clinpgx-database-logauaengstrom
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/LogauaEngstrom/claude-scientific-skills/tree/main/scientific-skills/clinpgx-database
Command: npx skills add https://github.com/LogauaEngstrom/claude-scientific-skills --skill clinpgx-database-logauaengstrom

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, and includes scripts (resource) and references (resource) components.

What problem does it solve?

ClinPGx consolidates pharmacogenomics knowledge from PharmGKB, CPIC, PharmCAT, and DPWG into a single access point, enabling researchers and clinicians to query gene–drug interactions, dosing guidelines, allele functions, and regulatory labels to support precision medicine.

Core Features & Use Cases

  • Gene queries: retrieve pharmacogenes, functions, and clinical annotations.
  • Drug/chemical queries: search pharmacogenomic drug information and labels.
  • CPIC guidelines: access dosing recommendations and implementation considerations.
  • Allele/variant data: obtain allele frequencies, functions, and phenotype mappings.
  • Clinical annotations: review evidence and literature links for gene–drug relationships.
  • Pathways and labels: explore pharmacokinetic/pharmacodynamic pathways and regulatory labels.
  • PharmDOG integration: support phenotype interpretation and dosage decisions.
  • Use cases: clinical decision support, research panel design, and trial screening.

Quick Start

Query the ClinPGx API to retrieve gene–drug interactions, guidelines, and allele data for rapid insight.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query pharmacogenomics gene-drug interactions for clinical decision support?▼

You can query pharmacogenomics gene-drug interactions by accessing the ClinPGx REST API to retrieve clinical annotations, CPIC guidelines, and allele data for precision medicine decisions.

What pharmacogenomics data sources are available through ClinPGx?▼

ClinPGx consolidates pharmacogenomics knowledge from PharmGKB, CPIC, PharmCAT, and DPWG into a single access point for querying gene-drug interactions, dosing guidelines, and regulatory labels.

Can I retrieve CPIC dosing guidelines and drug labels using a Python script?▼

Yes, you can retrieve CPIC dosing guidelines and regulatory drug labels using modular Python functions that access rate-limited REST API endpoints with built-in caching and error handling.

How do I get allele frequencies and phenotype mappings for pharmacogenes?▼

You can obtain allele frequencies, functions, and phenotype mappings by querying the dedicated allele and variant data endpoints provided through the ClinPGx API integration.

Does this pharmacogenomics tool support pharmacokinetic and pharmacodynamic pathway exploration?▼

Yes, the tool supports exploring pharmacokinetic and pharmacodynamic pathways by querying the pathway endpoints to retrieve detailed gene-drug interaction networks for research and trial design.

What are the limitations of using the ClinPGx database for clinical trial screening?▼

The utility is constrained by rate limits on the REST API, requiring caching and error handling for large-scale pharmacogenomics queries during clinical trial screening and research panel design.

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