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clinpgx-database

Query ClinPGx pharmacogenomics data for gene-drug interactions, CPIC guidelines, and alleles.

1|Updated Mar 4, 2026
Search Tags:#clinical-annotations#pharmacogenomics#alleles#gene-drug#cpic#clinpgx
One-click install
npx skills add https://github.com/Hung-3008/agusta --skill clinpgx-database-hung-3008
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/Hung-3008/agusta/tree/main/.agents/skills/clinpgx-database
Command: npx skills add https://github.com/Hung-3008/agusta --skill clinpgx-database-hung-3008

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

ClinPGx pharmacogenomics data access supports informed, genotype-guided prescribing by delivering gene–drug interactions, allele functions, and CPIC guidelines to clinicians and researchers.

Core Features & Use Cases

  • Query pharmacogene information, gene–drug interactions, CPIC guidelines, and drug labels for precision medicine.
  • Retrieve allele frequencies, phenotypes, and clinical annotations to support dosing decisions and safety assessments.
  • Use Cases: Integrate pharmacogenomics data into decision support tools, research pipelines, and patient education materials.

Quick Start

Use ClinPGx to look up CPIC-guided interactions for a patient’s genotype.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query CPIC guidelines and gene-drug interactions for pharmacogenomics clinical decision support?▼

You can look up CPIC-guided gene-drug interactions for a patient's genotype by querying the ClinPGx pharmacogenomics database endpoints, which include gene, drug, allele, clinicalAnnotation, and guideline endpoints to support precision medicine decisions.

How do I retrieve allele frequencies and phenotypes for pharmacogenomics research?▼

Retrieve allele frequencies and phenotypes by querying the ClinPGx allele and clinicalAnnotation endpoints, which provide pharmacogenomics data to support dosing decisions and safety assessments. This enables pharmacogenomics research and patient education materials.

Does the ClinPGx pharmacogenomics database require authentication to access clinical annotations?▼

The ClinPGx pharmacogenomics database supports optional authentication for accessing clinical annotations and gene-drug interaction endpoints. It enforces rate limiting and operates under a CC BY-SA 4.0 license for data distribution.

Can I use Python requests to access pharmacogene information and drug labels programmatically?▼

Yes, you can use Python requests to programmatically access pharmacogene information and drug labels from the ClinPGx database. The Skill exposes RESTful endpoints including gene, chemical, drugLabel, variant, and pathway for integration into research pipelines.

What are the limitations of using ClinPGx data for genotype-guided dosing?▼

Limitations include rate limiting on API endpoints and data licensing under CC BY-SA 4.0, requiring attribution for pharmacogenomics data used in genotype-guided dosing. The database provides gene-drug interaction data but requires clinical interpretation.

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