clinpgx-database

Query ClinPGx pharmacogenomics data for genes, alleles, and CPIC guidelines.

1|Updated Mar 19, 2026
One-click install
npx skills add https://github.com/JosephWoodall/noosphere --skill clinpgx-database-josephwoodall
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/JosephWoodall/noosphere/tree/main/.agent/skills/clinpgx-database
Command: npx skills add https://github.com/JosephWoodall/noosphere --skill clinpgx-database-josephwoodall

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

ClinPGx provides a centralized, programmatic access to pharmacogenomics data to inform genotype-guided therapy decisions.

Core Features & Use Cases

  • Gene, chemical, and pathway queries via ClinPGx REST API for pharmacogenomics workflows.
  • CPIC/DPWG guidelines, allele functions, and clinical annotations to support precision medicine.
  • Use cases include decision support for drug selection and dosing, research analyses, and panel design.

Quick Start

Run the ClinPGx API Query helper to fetch CYP2D6 gene info and CPIC guidelines for clopidogrel.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query CPIC guidelines for pharmacogenomics data programmatically?

You can query CPIC guidelines for pharmacogenomics data by making rate-limited HTTP requests via the ClinPGx REST API, which retrieves gene, allele, and clinical annotation information to support precision medicine dosing decisions.

Can I retrieve allele frequencies and gene-drug interaction data for precision medicine?

Yes, retrieving allele frequencies and gene-drug interaction data for precision medicine is supported through gene-centric and drug queries via the ClinPGx REST API, returning JSON-friendly structures for downstream analysis.

Do I need the requests library to access ClinPGx pharmacogenomics data?

Yes, the requests library is required as a dependency to access ClinPGx pharmacogenomics data, because the Skill implements HTTP requests, handles retries, and uses caching to manage API interactions.

What's the best way to get CYP2D6 gene info and clopidogrel CPIC guidelines?

The best way to get CYP2D6 gene info and clopidogrel CPIC guidelines is to run the ClinPGx API Query helper, which fetches specific gene data and relevant CPIC guidelines for drug selection workflows.

Does this pharmacogenomics API approach support DPWG guidelines alongside CPIC guidelines?

Yes, this pharmacogenomics API approach supports both CPIC and DPWG guidelines, retrieving allele functions and clinical annotations to inform genotype-guided drug selection and dosing across different guideline sources.

Are there limitations when querying large sets of pharmacogenomics alleles via the ClinPGx API?

Querying large sets of pharmacogenomics alleles via the ClinPGx API is managed by built-in rate limiting, retry handling, and caching mechanisms to prevent request failures, though results are structured as JSON-friendly exports for downstream analysis.