clinpgx-database

Query gene-drug interactions and clinical guidelines from the ClinPGx database.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill clinpgx-database-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/clinpgx-database
Command: npx skills add https://github.com/yf8578/clawomics --skill clinpgx-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides access to comprehensive pharmacogenomic data, enabling precise interpretation of how genetic variations influence drug response and guiding personalized treatment decisions.

Core Features & Use Cases

  • Gene-Drug Interaction Queries: Retrieve detailed information on how specific genes affect drug metabolism, efficacy, and toxicity.
  • Clinical Guideline Access: Access evidence-based recommendations from CPIC and other bodies for genotype-guided dosing.
  • Use Case: A clinician can use this Skill to quickly determine the appropriate warfarin dosage for a patient based on their CYP2C9 and VKORC1 genotypes, referencing CPIC guidelines.

Quick Start

Use the clinpgx-database skill to find gene-drug interactions for CYP2D6 and codeine.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query pharmacogenomic gene-drug interactions for clinical guidelines?

To query pharmacogenomic gene-drug interactions, this Skill provides programmatic access to the ClinPGx database, retrieving detailed information on how specific genes affect drug metabolism, efficacy, and toxicity. It leverages a Python requests library for REST API interaction to fetch the data.

What is the best way to access CPIC clinical guidelines for genotype-guided dosing?

The best way to access CPIC clinical guidelines for genotype-guided dosing is by using this Skill to retrieve evidence-based recommendations from the ClinPGx database. It allows you to programmatically pull clinical guidelines to inform personalized treatment decisions based on patient genotypes.

Can I use Python requests to retrieve drug labels and allele functions from a pharmacogenomics database?

Yes, you can use Python requests to retrieve drug labels and allele functions from a pharmacogenomics database. This Skill integrates with the requests library for REST API interaction, enabling you to query and extract specific pharmacogenomic data points seamlessly.

How does pharmacogenomics support precision medicine and drug response variations?

Pharmacogenomics supports precision medicine by interpreting how genetic variations influence drug response variations. This Skill enables genotype-guided dosing decisions by providing access to comprehensive gene-drug interaction data, helping clinicians understand individual patient metabolic profiles.

Do I need the requests library to use the ClinPGx database skill?

Yes, you need the requests library installed to use this Skill, as it relies on Python requests for REST API interaction with the ClinPGx database. This dependency is required to programmatically query gene-drug interactions, allele functions, and clinical guidelines.

What are the limitations of using a pharmacogenomics database for clinical dosing decisions?

A limitation of using a pharmacogenomics database for clinical dosing decisions is that it provides programmatic data access rather than integrated clinical decision support within a patient EHR. Users must manually interpret gene-drug interactions and clinical guidelines to apply dosing recommendations to individual patient contexts.