clinpgx-database

Query the ClinPGx pharmacogenomics database for gene-drug interactions and CPIC guidelines.

8|Updated Jan 13, 2026

Search Tags:#database #drug interactions #genetics #pharmacogenomics #clinical guidelines #precision medicine

Ready to run

npx skills add https://github.com/hxk622/TokenDance --skill clinpgx-database-hxk622

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/hxk622/TokenDance/tree/main/backend/app/skills/builtin/scientific/database/clinpgx-database
Command: npx skills add https://github.com/hxk622/TokenDance --skill clinpgx-database-hxk622

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides access to comprehensive pharmacogenomics data, enabling precise, genotype-guided medication decisions and advancing precision medicine.

Core Features & Use Cases

Gene-Drug Interactions: Query how genetic variations affect drug response, efficacy, and toxicity.
Clinical Guidelines: Access evidence-based CPIC guidelines for actionable dosing recommendations.
Allele & Variant Data: Retrieve detailed information on genetic variants and their functional impact.
Use Case: A clinician can use this Skill to check if a patient's CYP2C19 genotype requires an alternative antiplatelet therapy to clopidogrel, based on CPIC guidelines.

Quick Start

Query the ClinPGx API for gene-drug interactions related to CYP2D6 and codeine.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I query pharmacogenomics data for gene-drug interactions?▼

You can query pharmacogenomics data for gene-drug interactions programmatically through the ClinPGx API to retrieve information on how genetic variations affect drug response, efficacy, and toxicity.

Can I access CPIC clinical guidelines for genotype-guided dosing decisions?▼

Yes, you can access evidence-based CPIC clinical guidelines through the pharmacogenomics database to support precise, genotype-guided dosing recommendations and precision medicine decisions.

What pharmacogenomics data is available for allele functions and genetic variants?▼

The pharmacogenomics database provides detailed information on genetic variants and their functional impact, allowing you to retrieve specific allele functions and variant data for clinical analysis.

How do I check if a patient's genotype requires alternative therapy based on CPIC guidelines?▼

You can check if a patient's genotype requires alternative therapy by querying the pharmacogenomics database with the specific gene, such as CYP2C19, to retrieve CPIC guidelines and drug interaction data for clinical decisions.

Does the pharmacogenomics database work with Python requests for API queries?▼

Yes, the pharmacogenomics database API supports programmatic access using Python and the requests library, enabling automated queries for drug labels, allele functions, and gene-drug interaction data.

What are the limitations of using a pharmacogenomics database for precision medicine?▼

While the pharmacogenomics database provides CPIC guidelines and gene-drug interaction data, users must interpret allele functions and variant data within their specific clinical context to ensure safe precision medicine outcomes.