db-clinpgx

Query ClinPGx for gene-drug interactions, CPIC guidelines, allele functions, and variant data.

Updated Mar 13, 2026
One-click install
npx skills add https://github.com/biomaps-infra/blender-opencode --skill db-clinpgx
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: db-clinpgx
Source: https://github.com/biomaps-infra/blender-opencode/tree/main/.opencode/skills/db-clinpgx
Command: npx skills add https://github.com/biomaps-infra/blender-opencode --skill db-clinpgx

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides access to the ClinPGx database, a comprehensive resource for pharmacogenomic data, enabling users to query gene-drug interactions, clinical guidelines, and allele functions to inform precision medicine and genotype-guided dosing.

Core Features & Use Cases

  • Gene-Drug Interaction Queries: Understand how genetic variations affect drug response.
  • CPIC Guideline Access: Retrieve evidence-based clinical practice guidelines.
  • Allele and Variant Information: Get detailed data on genetic variants and their functional impact.
  • Use Case: A clinician can use this Skill to quickly check if a patient's genotype for CYP2C19 necessitates an alternative antiplatelet therapy to clopidogrel, based on CPIC guidelines.

Quick Start

Use the db-clinpgx skill to find gene-drug pairs for CYP2D6 and codeine.

Frequently Asked Questions about db-clinpgx

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I find CPIC guidelines for gene-drug interactions in pharmacogenomics?

To find CPIC guidelines for gene-drug interactions, you can query the ClinPGx database to retrieve evidence-based clinical practice guidelines and pharmacogenomic data for precision medicine applications. This supports clinical decision making by providing genotype-guided dosing recommendations.

What pharmacogenomic data is available for variant allele functions?

Pharmacogenomic data for variant allele functions includes detailed information on genetic variants and their functional impact on drug response. The ClinPGx database provides this allele and variant data to inform genotype-guided dosing and clinical decisions.

Can I check if a CYP2C19 genotype requires alternative therapy to clopidogrel?

You can check if a CYP2C19 genotype requires alternative antiplatelet therapy to clopidogrel by querying gene-drug interactions and CPIC guidelines. The database enables clinicians to retrieve clinical practice guidelines for precision medicine and clinical decision support.

How do I query ClinPGx for CYP2D6 and codeine gene-drug pairs?

To query ClinPGx for CYP2D6 and codeine gene-drug pairs, use the database query function to retrieve pharmacogenomic information. This provides gene-drug interaction data and clinical guidelines to understand how genetic variations affect drug response for precision medicine.

When do I need pharmacogenomic information for clinical decision support?

You need pharmacogenomic information for clinical decision support when determining genotype-guided dosing and understanding gene-drug interactions. The database provides CPIC guidelines, allele functions, and variant data to inform precision medicine applications and clinical practice guidelines.

Does the pharmacogenomics database support genotype-guided dosing for precision medicine?

The pharmacogenomics database supports genotype-guided dosing for precision medicine by providing comprehensive gene-drug interaction data, CPIC guidelines, and allele functional impact information. This enables clinical decision support for tailoring therapies based on genetic variations.