CPIC

Query the CPIC REST API for pharmacogenomic dosing guidelines by drug or gene.

130|4|Updated Mar 13, 2026

Search Tags:#evidence #guidelines #pharmacogenomics #pgx #gene-drug #cpic #drug-dosing

Ready to run

npx skills add https://github.com/QSong-github/DrugClaw --skill cpic

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: CPIC
Source: https://github.com/QSong-github/DrugClaw/tree/main/skills/drug_knowledgebase/cpic
Command: npx skills add https://github.com/QSong-github/DrugClaw --skill cpic

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

CPIC provides pharmacogenomic guidelines linking genes/variants to drug dosing to support evidence-based prescribing.

Core Features & Use Cases

Drug metadata: drug identifiers, flowcharts, and related data.
Guidelines: dosing recommendations based on CPIC/ClinPGx levels.
Gene–drug pairs: curated associations for personalized therapy.
Dosing recommendations: phenotype-specific adjustments with citations.

Quick Start

Query CPIC with a drug name or gene symbol to retrieve guidelines, gene–drug pairs, and dosing recommendations via the REST API.

Frequently Asked Questions about CPIC

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I retrieve pharmacogenomic drug dosing guidelines for a specific gene or medication?▼

Retrieve pharmacogenomic drug dosing guidelines by querying with a drug name or gene symbol to get phenotype-specific recommendations, gene-drug pairs, and citations via the REST API.

What are CPIC gene-drug pairs and how do they support personalized therapy?▼

Gene-drug pairs are curated associations linking genetic variants to drug responses, supporting personalized therapy by providing evidence-based prescribing decisions and metadata for targeted treatments.

Can I query pharmacogenomic guidelines using a standard drug name instead of an internal identifier?▼

Yes, the system resolves standard drug names to internal drug IDs automatically, allowing you to query pharmacogenomic guidelines directly using familiar medication names.

What happens when the pharmacogenomic REST API is offline during a drug dosing query?▼

When the REST API is offline, the system handles offline fallbacks to ensure structured results with dosing recommendations and evidence are still returned for pharmacogenomic queries.

How do I find phenotype-specific dosing recommendations with clinical evidence and citations?▼

Find phenotype-specific dosing recommendations by querying a drug or gene, returning structured results that include clinical evidence levels and citations based on CPIC and ClinPGx standards.