skills.rest
pur3v4d3r
pur3v4d3rCOMMUNITY
Explore all skills by this author →
GitHub

clinpgx-database

Query ClinPGx REST API for gene-drug interactions, CPIC guidelines, and allele functions.

6|Updated Dec 30, 2025
Search Tags:#drug-labels#pharmacogenomics#alleles#gene-drug#pharmacogenetics#clinpgx#cpic-guidelines
One-click install
npx skills add https://github.com/pur3v4d3r/pur3-pkb-codebase --skill clinpgx-database-pur3v4d3r
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/pur3v4d3r/pur3-pkb-codebase/tree/main/.claude/skills/__scientific-skills/clinpgx-database
Command: npx skills add https://github.com/pur3v4d3r/pur3-pkb-codebase --skill clinpgx-database-pur3v4d3r

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

ClinPGx consolidates curated pharmacogenomics data from PharmGKB, CPIC, PharmCAT, and DPWG. This skill enables researchers and clinicians to quickly query gene-drug interactions, CPIC guidelines, allele functions, and drug-label information to support precision dosing and genotype-guided therapy.

Core Features & Use Cases

  • Retrieve gene-drug interactions and clinical annotations for pharmacogenes (e.g., CYP2D6, TPMT)
  • Access CPIC guidelines and dosing recommendations for genotype-driven therapy
  • Explore allele function, population frequencies, and pharmacogenomic variant annotations
  • Retrieve drug labels and pathway information for comprehensive clinical decision support

Quick Start

Query CYP2D6 and clopidogrel data to retrieve allele functions, CPIC guidance, and dosing recommendations.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve CPIC guidelines and gene-drug interactions for precision dosing?▼

You can retrieve CPIC guidelines and gene-drug interactions by querying the ClinPGx REST API endpoints for geneDrugPair, guideline, and clinicalAnnotation data. This skill provides structured outputs with rate limiting and caching to support precision medicine workflows.

Can I access pharmacogenomics allele functions and variant annotations through an API?▼

Yes, you can query the allele and variant endpoints of the ClinPGx API. This skill retrieves allele functions, population frequencies, and pharmacogenomic variant annotations using structured REST API requests with built-in caching.

How do I get drug labels and pathway information for pharmacogenes like CYP2D6?▼

Query the drugLabel and pathway endpoints via the ClinPGx API to retrieve comprehensive clinical decision support data. This skill fetches structured outputs for specific pharmacogenes like CYP2D6, including relevant drug-label annotations and pathway details.

Does this pharmacogenomics database tool require any specific dependencies or environments?▼

The skill requires the Python requests library to handle REST API access. It is designed for researchers and clinicians needing structured pharmacogenomics data retrieval, providing built-in rate limiting and caching to manage API query loads.

What's the best way to query clinical annotations and dosing recommendations for genotype-driven therapy?▼

The best way is to query the guideline and clinicalAnnotation endpoints provided by the ClinPGx API. This skill enables retrieval of CPIC dosing recommendations and clinical annotations for genotype-driven therapy, returning structured outputs for precision medicine workflows.

Related Skills

Explore More Data & Analytics Skills→
yf8578yf8578
1

clinpgx-database

Query gene-drug interactions and clinical guidelines from the ClinPGx database.

Community
Intermediate
Hung-3008Hung-3008
1

clinpgx-database

Query ClinPGx pharmacogenomics data for gene-drug interactions, CPIC guidelines, and alleles.

Community
Advanced
jiaxiaojunQAQjiaxiaojunQAQ
75

clinpgx-database

Query ClinPGx pharmacogenomics data for gene-drug interactions and CPIC guidelines.

Community
Advanced
HolobiomicsLabHolobiomicsLab
4

clinpgx-database

Retrieve pharmacogenomics data from ClinPGx via its REST API.

Official
Advanced