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codon-optimization

Official

Codon-optimize DNA for any host with precision.

Education & Research#bioinformatics#protein#codon-optimization#dna#biotechnology#codon-harmonization#reverse-translation
Authorcultivarium
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill enables researchers to optimize coding sequences for expression in a host by recoding DNA to preferred codons, increasing protein yield and compatibility with host translation.

Core Features & Use Cases

  • Codon optimization to maximize CAI for a target organism or to match a provided codon usage table.
  • Codon harmonization to preserve translational pausing patterns and improve folding for complex proteins.
  • Reverse translation from protein sequences to DNA using a chosen codon usage profile.
  • Generate codon usage tables from GenBank or FASTA genomes and perform end-to-end workflows.

Quick Start

Provide a DNA sequence and a target organism or codon usage table to start optimizing.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: codon-optimization
Download link: https://github.com/cultivarium/hermes-starter-kit/archive/main.zip#codon-optimization

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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