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cosmic-database

Query COSMIC cancer genomics data for gene mutations and structural variants.

Updated May 10, 2026
Search Tags:#database#bioinformatics#genomics#mutation#cancer-gene#cancer
One-click install
npx skills add https://github.com/Imad-Oute/ResearchForge --skill cosmic-database-imad-oute
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: cosmic-database
Source: https://github.com/Imad-Oute/ResearchForge/tree/main/OpenSource-Projects/claude-scientific-skills/scientific-skills/cosmic-database
Command: npx skills add https://github.com/Imad-Oute/ResearchForge --skill cosmic-database-imad-oute

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides seamless access to the extensive COSMIC cancer mutation database, enabling researchers to retrieve detailed genomics data efficiently.

Core Features & Use Cases

  • Data Retrieval: Download mutation, gene census, structural variants, copy number alterations, and gene expression datasets.
  • Research Application: Use for identifying cancer driver genes, analyzing mutational signatures, and integrating COSMIC data into annotation pipelines.
  • Use Case: Researchers can pull mutation data for a specific gene, filter for tumor types, and incorporate findings into publications or further bioinformatics workflows.

Quick Start

Request the mutation data for a specific gene to analyze its mutation frequency across samples.

Frequently Asked Questions about cosmic-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve cancer mutation data from the COSMIC database for a specific gene?▼

To retrieve cancer mutation data, query the COSMIC database by specifying a target gene to analyze its mutation frequency across samples. You can download mutation datasets, filter for tumor types, and integrate findings into bioinformatics workflows.

Can I use this to analyze mutational signatures and structural variants in cancer genomics?▼

Yes, you can analyze mutational signatures and explore structural variants in cancer genomics. The skill provides programmatic access to retrieve structural variants, copy number alterations, and gene expression datasets for comprehensive research.

What datasets are available for cancer research workflows through COSMIC access?▼

Available datasets include gene mutation data, the gene census, structural variants, copy number alterations, and gene expression datasets. These support identifying cancer driver genes and integrating data into annotation pipelines.

How do I filter COSMIC mutation data by tumor type for bioinformatics analysis?▼

You can filter COSMIC mutation data by tumor type by requesting data for a specific gene and applying filters within your bioinformatics workflow. This allows targeted analysis of mutation frequency across relevant cancer samples.

Do I need any dependencies to access COSMIC genomics data programmatically?▼

No dependencies are required to access COSMIC genomics data programmatically. The skill operates independently using scripts and references to facilitate complex cancer genomics data analysis workflows.

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