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cosmic-database

Download cancer mutation data, gene census, and mutational signatures from the COSMIC database.

Updated Jan 10, 2026
Search Tags:#bioinformatics#mutational signatures#cancer genomics#cosmic#mutation data#gene census
One-click install
npx skills add https://github.com/robinbarvaag/poynt --skill cosmic-database-robinbarvaag
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: cosmic-database
Source: https://github.com/robinbarvaag/poynt/tree/main/.github/skills/cosmic-database
Command: npx skills add https://github.com/robinbarvaag/poynt --skill cosmic-database-robinbarvaag

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, pysam, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the COSMIC database, enabling researchers to download and analyze comprehensive cancer mutation data, gene lists, and signatures.

Core Features & Use Cases

  • Data Download: Download various COSMIC datasets including mutations, gene census, and mutational signatures.
  • Bioinformatics Integration: Facilitates the integration of COSMIC data into bioinformatics pipelines for cancer research and precision oncology.
  • Use Case: Download the Cancer Gene Census to identify known cancer-driving genes for targeted therapy selection in a patient's tumor.

Quick Start

Use the cosmic-database skill to download the Cancer Gene Census file.

Frequently Asked Questions about cosmic-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I download COSMIC cancer mutation data for bioinformatics analysis?▼

You can download COSMIC cancer mutation data by using this Skill to programmatically access the database, retrieve curated genomic and clinical annotations, and integrate them directly into your research pipelines.

What is the Cancer Gene Census and how do I access it for precision oncology?▼

The Cancer Gene Census is a curated list of known cancer-driving genes. You can access it through this Skill to identify targetable genes for precision oncology and targeted therapy selection.

Do I need authentication credentials to retrieve mutational signatures from the COSMIC database?▼

Yes, retrieving mutational signatures and other COSMIC data requires authentication credentials and specific file paths to successfully access and download the curated datasets.

Can I use pandas and pysam to process COSMIC mutation data in cancer genomics pipelines?▼

Yes, this Skill integrates with pandas and pysam to facilitate the incorporation of downloaded COSMIC mutation data and gene census files into existing cancer genomics and bioinformatics pipelines.

What types of cancer genomics datasets can I retrieve using this COSMIC database integration?▼

You can retrieve comprehensive datasets including cancer mutation data, the Cancer Gene Census, and mutational signatures, all providing curated genomic and clinical annotations for research.

Are there limitations when downloading large COSMIC datasets for cancer research?▼

This Skill requires proper authentication and specific file paths for data retrieval. Users must ensure their environment supports the dependencies like requests, pandas, and pysam for successful integration.

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