skills.rest
jaechang-hits
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ddinter-database

Queries DDinter REST API for drug-drug interaction severity, mechanisms, and recommendations.

298|27|Updated Feb 18, 2026
Search Tags:#drug interactions#clinical decision support#pharmacology#pharmaceuticals#drug safety#ddi
One-click install
npx skills add https://github.com/jaechang-hits/SciAgent-Skills --skill ddinter-database
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: ddinter-database
Source: https://github.com/jaechang-hits/SciAgent-Skills/tree/main/skills/structural-biology-drug-discovery/ddinter-database
Command: npx skills add https://github.com/jaechang-hits/SciAgent-Skills --skill ddinter-database

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, matplotlib, networkx, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill helps identify and understand potential drug-drug interactions (DDIs), crucial for patient safety and effective medication management.

Core Features & Use Cases

  • DDI Search: Query interactions between specific drug pairs or retrieve all interactions for a given drug.
  • Severity & Mechanism: Get details on interaction severity (major, moderate, minor) and underlying mechanisms (PK/PD).
  • Use Case: A pharmacist can use this Skill to quickly check if a new prescription for a patient already on multiple medications poses a major interaction risk, providing immediate clinical guidance.

Quick Start

Use the ddinter-database skill to check for interactions between warfarin and aspirin.

Frequently Asked Questions about ddinter-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I check drug-drug interactions using a REST API?▼

To check drug-drug interactions, query the DDInter database via a REST API to retrieve interaction data, severity levels, mechanisms, and clinical recommendations for specific drug pairs or individual drugs.

What information is included in drug-drug interaction data?▼

Drug-drug interaction data includes severity levels (major, moderate, minor), underlying pharmacokinetic and pharmacodynamic mechanisms, and clinical recommendations to guide patient safety and medication management.

Can I retrieve all interactions for a single drug across a large database?▼

Yes, you can retrieve all interactions for a specific drug by searching with a drug name or ID, accessing over 1.7 million interactions across 2,400+ drugs without requiring any authentication.

How do I find the interaction severity and mechanism for a drug pair?▼

Search for the specific drug pair to retrieve detailed interaction severity levels and underlying PK/PD mechanisms, providing immediate clinical guidance for medication safety.

Do I need an API key to query clinical decision support data for drug safety?▼

No, querying the drug-drug interaction database requires no authentication, allowing direct access to retrieve interaction severity, mechanisms, and clinical recommendations without an API key.

What is the best way to visualize a network of drug interactions?▼

You can use networkx and matplotlib to visualize drug-drug interaction networks, mapping drug pairs and severity levels to identify major interaction risks across patient medication regimens.

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