mecddi-query

Retrieve mechanism-based drug-drug interactions from MecDDI by drug name or ID.

130|4|Updated Mar 13, 2026
One-click install
npx skills add https://github.com/QSong-github/DrugClaw --skill mecddi-query
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: mecddi-query
Source: https://github.com/QSong-github/DrugClaw/tree/main/skills/ddi/mecddi
Command: npx skills add https://github.com/QSong-github/DrugClaw --skill mecddi-query

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Query MecDDI to quickly identify mechanism-based drug-drug interactions for given drug names or MecDDI IDs, delivering mechanism context and traceable references to support clinical or research decisions.

Core Features & Use Cases

  • Input auto-detection: accepts either MecDDI Drug IDs (D1234) or drug names and matches via exact ID or substring on names.
  • Mechanism-aware results: returns interaction pairs with mechanism category (PK/PD) and involved enzymes or transporters.
  • Use Case: a pharmacology researcher asks whether imatinib interacts with another drug and reviews the mechanism and supporting sources.

Quick Start

Query MecDDI with a drug name or MecDDI ID to retrieve mechanism-based DDIs.

Frequently Asked Questions about mecddi-query

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve mechanism-based drug-drug interactions for pharmacokinetic analysis?

Query the MecDDI database by providing either a drug name or a specific MecDDI ID to retrieve mechanism-based drug-drug interactions. Results include the interaction pair, PK/PD mechanism category, and involved enzymes or transporters.

Can I search for drug interactions using both drug names and specific MecDDI IDs?

Yes, the query system uses input auto-detection to accept both MecDDI Drug IDs and drug names, matching via exact ID lookup or substring matching on names to retrieve interaction data.

What data format is required to load MecDDI data for batch querying?

You need to load MecDDI data from TSV or CSV files to enable querying. Once loaded, you can perform single or batch queries to retrieve mechanism-based drug-drug interactions.

How do I get pharmacodynamic and pharmacokinetic mechanism details for clinical decision support?

Query MecDDI with a specific drug name or ID to retrieve PK/PD mechanism categories, involved enzymes or transporters, and traceable references. This mechanism context directly supports clinical decision-making and safety assessment.

Does MecDDI querying provide supporting references for identified drug interaction mechanisms?

Yes, querying MecDDI returns mechanism context along with traceable references for each identified drug-drug interaction. These supporting sources help validate pharmacology research and clinical safety assessments.