scientific-clinical-pharmacology
CommunityClinical pharmacology PK/PD modeling workflow.
Authornahisaho
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This skill provides an integrated workflow for modeling drug kinetics and dynamics, combining population PK, physiologically based PK, and pharmacodynamic modeling to support dose optimization and clinical decisions.
Core Features & Use Cases
- PopPK estimation: NLME-style parameter estimation from sparse data using a coherent modeling framework.
- PBPK simulations: Physiologically informed simulations to predict drug disposition across tissues and populations.
- Dose optimization & TDM: Guidance for therapeutic drug monitoring and dosing adjustments in special populations (renal/hepatic impairment, pediatrics).
- PD modeling: Emax/Sigmoid PD fitting and PK/PD integration for clinical decision support.
- End-to-end pipeline: From data preprocessing to simulation outputs and decision-support signals.
Quick Start
Run a complete clinical pharmacology pipeline to estimate PopPK, perform TDM-based dosing recommendations, and simulate PK/PD outcomes for your dataset.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: scientific-clinical-pharmacology Download link: https://github.com/nahisaho/satori/archive/main.zip#scientific-clinical-pharmacology Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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