design-base-editor-sgrnas
CommunityDesign precise base editor sgRNAs for genes.
AuthorMDhewei
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Designing base editor sgRNAs for a target gene to enable precise nucleotide changes with minimized bystander edits.
Core Features & Use Cases
- Automated base editor sgRNA design across human, mouse, and monkey
- PAM-aware scanning & editing window filtering to identify guides with editable bases and minimal bystander edits
- Output & visualization: ranked guide table, top guides, bystander report, and editing heatmaps
Quick Start
Provide a gene symbol, organism, and editor to generate a ranked list of base editor sgRNAs for that gene.
Dependency Matrix
Required Modules
numpypandasmatplotlibrequests
Components
scripts
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: design-base-editor-sgrnas Download link: https://github.com/MDhewei/bioinfor-claw/archive/main.zip#design-base-editor-sgrnas Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
Agent Skills Search Helper
Install a tiny helper to your Agent, search and equip skill from 471,000+ vetted skills library on demand.