/design-round — Complete Round Lifecycle

Orchestrate a complete protein design round from generation to publishing.

Updated Feb 27, 2026
One-click install
npx skills add https://github.com/alex-hh/in-silico-pgdh --skill design-round-complete-round-lifecycle
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: /design-round — Complete Round Lifecycle
Source: https://github.com/alex-hh/in-silico-pgdh/tree/main/.claude/skills/design-round
Command: npx skills add https://github.com/alex-hh/in-silico-pgdh --skill design-round-complete-round-lifecycle

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill automates the entire end-to-end lifecycle of a protein design campaign round, from initial design generation to final publication.

Core Features & Use Cases

  • End-to-End Orchestration: Manages the complete workflow: design, synchronization, evaluation (CPU & GPU), and publishing.
  • Multi-Tool Support: Integrates with various design tools like BoltzGen and RFdiffusion3.
  • Iterative Improvement: Facilitates a structured approach to design rounds, enabling analysis and planning for subsequent rounds.
  • Use Case: A researcher can initiate a new round of protein binder design targeting a specific protein, and this Skill will handle submitting jobs, collecting results, evaluating them, and updating the project dashboard.

Quick Start

Execute the full design round lifecycle for the current round N.

Frequently Asked Questions about /design-round — Complete Round Lifecycle

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I automate a complete protein design campaign round from generation to publishing?

Automate a complete protein design campaign round by orchestrating design generation, result synchronization, multi-stage CPU and GPU evaluation, and findings publication. This workflow manages iterative design processes by advancing round numbers and updating project documentation automatically.

What is the best way to manage iterative protein design rounds and update project dashboards?

Managing iterative protein design rounds involves advancing round numbers, submitting jobs, collecting results, evaluating them, and updating the project dashboard. This lifecycle orchestration enables structured analysis and planning for subsequent computational biology design rounds.

Does protein design round orchestration work with BoltzGen and RFdiffusion3?

Protein design round orchestration works with multi-tool support, integrating design tools like BoltzGen and RFdiffusion3. It coordinates these tools within a full lifecycle workflow that includes design generation, synchronization, evaluation, and publishing.

Do I need Lyceum integration to submit jobs for computational biology design rounds?

Lyceum integration is required for job submission during computational biology design rounds. The workflow relies on Lyceum to manage job submission while utilizing local scripts for data handling and page generation.

Can I run multi-stage CPU and GPU evaluation for protein binder design in one workflow?

Multi-stage CPU and GPU evaluation for protein binder design is supported within a single workflow. The orchestration handles submitting jobs, collecting results, and executing both evaluation stages before publishing the final findings.

How do I start a new round of protein binder design targeting a specific protein?

Start a new round of protein binder design by initiating the lifecycle for the current round N. The orchestration handles submitting design generation jobs, collecting results, evaluating them, and publishing findings to the project dashboard.