design_sgrnas_by_gene
CommunityTop sgRNA guides for your genes.
AuthorMDhewei
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Retrieve CRISPR sgRNA candidates for a gene or gene list from the GuidePro genome-wide reference table, filtering and ranking results to support knockout design workflows across human, monkey, and mouse.
Core Features & Use Cases
- Retrieve sgRNA candidates for one gene, multiple genes, or a gene list from GuidePro.
- Automatically detect gene columns, handle gene lists from files, and output a ranked TSV with top guides per gene.
- Cache GuidePro reference locally, support --top-n-per-gene, optional deduplication, and optional summary reporting.
Quick Start
Run the skill to fetch GuidePro sgRNA candidates for a gene or gene list and output the top guides per gene
Dependency Matrix
Required Modules
pandas>=2.0.0
Components
scripts
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: design_sgrnas_by_gene Download link: https://github.com/MDhewei/bioinfor-claw/archive/main.zip#design-sgrnas-by-gene Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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