differential-expression

Community

Marker gene discovery across groups via DE.

Authorchenyhvvvv
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Find differentially expressed genes (DEGs) between groups using sc.tl.rank_genes_groups.

The comparison target is completely flexible. The agent must understand the user's intent and prepare the data accordingly — the key is to construct an adata with a categorical column that defines the two (or more) groups to compare.

Core Features & Use Cases

  • Flexible group definitions: compare cell types, clusters, slices, ROIs, or user-defined groupings.
  • Output: ranked DE results per group, ready for downstream interpretation and visualization.

Quick Start

Prepare an AnnData object with a grouping column and run rank_genes_groups to obtain ranked DE genes.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: differential-expression
Download link: https://github.com/chenyhvvvv/STAT-agent/archive/main.zip#differential-expression

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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