drug-repurposing-strategist
CommunityFind repurposing candidates for oral mucositis.
Education & Research#knowledge graph#ranking#hypothesis generation#drug repurposing#mechanism of action#oral mucositis#target overlap
AuthorOpenSourcePharmaFoundation
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill reduces the time needed to generate testable hypotheses for Oral Mucositis (OM) by systematically linking OM-associated biology to targets and mechanisms of already approved drugs.
Core Features & Use Cases
- Target-overlap repurposing: Identifies OM-relevant genes and maps them to approved drugs via drug-target data to shortlist candidates with plausible target engagement.
- Mechanism-of-action alignment: Checks whether each candidate’s mechanism direction fits what OM needs across inflammatory, oxidative, and healing phases.
- Feasibility scoring and structured outputs: Ranks candidates using a weighted framework covering overlap strength, safety context, route compatibility, and evidence level, then produces consistent candidate reports.
Quick Start
Use the drug-repurposing-strategist skill to generate a ranked repurposing candidate report for approved OM-relevant drugs using the processed CSV datasets under data/processed/.
Dependency Matrix
Required Modules
None requiredComponents
Standard packageđŸ’» Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: drug-repurposing-strategist Download link: https://github.com/OpenSourcePharmaFoundation/ospf-ayurveda-kg/archive/main.zip#drug-repurposing-strategist Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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