drug-targets

Prioritize drug-targets using causal evidence from public records and Open Targets.

475|61|Updated May 28, 2026
One-click install
npx skills add https://github.com/exon-research/genomi --skill drug-targets
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: drug-targets
Source: https://github.com/exon-research/genomi/tree/main/skills/drug-targets
Command: npx skills add https://github.com/exon-research/genomi --skill drug-targets

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) components.

What problem does it solve?

This Skill streamlines the identification and prioritization of causal drug-targets, leveraging extensive public records and genetic information to assist in the decision-making process for clinical applications and research.

Core Features & Use Cases

  • Causal Drug-Target Prioritization: Analyzes records from public sources to identify potential drug targets for specific diseases.
  • Gene and Mechanism Analysis: Provides detailed information about genes and their potential relationships with drugs and disease mechanisms.
  • Clinical Drug-Target Retrieval: Accesses disease-scoped clinical drug-target genes from Open Targets.
  • Use Case: For a given disease, quickly retrieve and compare candidate genes against direct drug-side context to assess potential therapeutic targets.

Quick Start

Retrieve drug targets for asthma by querying phenotype.retrieve_disease_drug_targets with the disease 'asthma' and a list of candidate genes.

Frequently Asked Questions about drug-targets

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I prioritize causal drug-targets for a specific disease?

To prioritize causal drug-targets, query the Skill with a disease name and a list of candidate genes. It analyzes public records and mechanism genes to assess and compare potential therapeutic targets.

What is the best way to retrieve disease-specific drug-target genes using Open Targets?

You can retrieve disease-specific drug-target genes by calling the disease query function with the target phenotype. It accesses Open Targets to gather clinical drug-target evidence for the requested disease.

Can I use a custom candidate gene list to assess potential therapeutic targets?

Yes, you can input a custom candidate gene list. The Skill compares your genes against direct drug-target evidence and disease mechanisms to evaluate their viability as therapeutic targets.

How does genetic analysis evaluate causal relationships between drugs and diseases?

Genetic analysis evaluates causal relationships by cross-referencing public records, drug mechanisms, and direct drug-target evidence. This provides an accurate assessment of a gene's link to a disease.

Does drug-target prioritization work with drug class and mechanism data?

Yes, drug-target prioritization supports drug class and mechanism data. It utilizes direct drug-target evidence alongside mechanism genes to deliver a more accurate assessment of causal relationships.